Chemical Name: 2,3,4-Trimethoxybenzaldehyde
Synonyms: Benzaldehyde, 2,3,4-trimethoxy-
CAS Number: 34831-94-4
Molecular Formula: C10H12O4
Molecular Weight: 196.2 g/mol
Recommended Use: Research, chemical synthesis, specialty chemical applications
Manufacturer’s Information: Refer to supplier or vendor contact data for emergency phone number and addresses
GHS Classification: Acute toxicity (oral, category 4), Eye irritation (category 2A), Specific target organ toxicity - single exposure (category 3)
Label Elements: Signal Word: Warning. Pictograms: Exclamation mark
Hazard Statements: Harmful if swallowed. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: Avoid breathing dust, fumes, mist or vapors. Wash hands thoroughly after handling. Wear protective gloves, protective clothing, eye protection, and face protection. Use only outdoors or in a well-ventilated area.
Other Hazards: No available data on PBT/vPvB assessment. Not listed as a carcinogen by IARC, NTP, or OSHA.
Chemical Entity: 2,3,4-Trimethoxybenzaldehyde
Concentration: >98% (w/w)
Impurities/Other Components: Trace impurities under 1% each
CAS Number: 34831-94-4
EC Number: 252-250-8
Substance or Mixture: Pure substance
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Seek medical attention if symptoms persist.
Skin Contact: Wash skin thoroughly with plenty of water and soap. Remove contaminated clothing and wash before reuse. Seek medical advice for any irritation.
Eye Contact: Rinse cautiously with water for at least fifteen minutes. Remove contact lenses if present and easy to do. Obtain medical attention for persistent discomfort.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by medical personnel. Get medical help if feeling unwell.
Suitable Extinguishing Media: Foam, dry chemical, or carbon dioxide. Use water spray to cool containers.
Unsuitable Extinguishing Media: Direct water jet.
Specific Hazards from Fire: May release irritating fumes, carbon monoxide, carbon dioxide under fire conditions.
Protective Equipment: Firefighters should wear approved, self-contained breathing apparatus and complete protective gear.
Special Precautions: Evacuate area. Prevent runoff from entering watercourses or drains.
Personal Precautions: Evacuate non-essential personnel. Wear suitable respirator, gloves, eye and face protection.
Environmental Precautions: Take care to avoid contamination of soil, drains, and water sources.
Cleanup Methods: Absorb spill with inert absorbent material such as sand or earth. Scoop up and place in suitable container for disposal. Wash spill area thoroughly with water.
Disposal: Dispose of according to local, regional, national, and international guidelines.
Safe Handling: Avoid inhalation of dust, vapor, and mists. Do not swallow, avoid contact with skin and eyes. Use with adequate ventilation.
Hygiene Practices: Wash hands before breaks and at end of workday. Keep contaminated clothing away from other clothing.
Storage Conditions: Store in cool, dry, well-ventilated place. Keep container tightly closed and protect from direct sunlight and moisture.
Incompatible Materials: Strong acids, strong bases, oxidizing agents.
Storage Class: Chemical storage, non-flammable solids.
Engineering Controls: Use only in well-ventilated areas. Provide local exhaust at points of emission.
Personal Protection:
Appearance: Crystalline solid or powder
Color: White to off-white
Odor: Characteristic aromatic
Odor Threshold: Data not available
pH: Not applicable (solid)
Melting Point: 71-74°C
Boiling Point: 157-160°C at 18 mmHg
Flash Point: Above 100°C (closed cup method)
Evaporation Rate: Not determined
Flammability: Non-flammable in solid form
Vapor Pressure: Negligible at room temperature
Vapor Density: Not determined
Relative Density: 1.19 g/cm³
Solubility: Slightly soluble in water, readily soluble in organic solvents such as ethanol or ether
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: No data
Decomposition Temperature: Not available
Viscosity: Not applicable (solid)
Chemical Stability: Stable under standard temperatures and pressures.
Reactivity: Does not undergo hazardous reactions under normal conditions.
Hazardous Reactions: May react with strong oxidizing agents or acids.
Conditions to Avoid: Contact with moisture, elevated temperature, incompatible substances.
Incompatible Materials: Strong acids, bases, oxidizers.
Hazardous Decomposition Products: May emit carbon monoxide, carbon dioxide, and other irritating fumes if decomposed by heat or flame.
Acute Toxicity: Harmful if swallowed, causes irritation to respiratory tract and eyes, LD50 (oral, rat): Estimated 680 mg/kg
Skin Corrosion/Irritation: May cause minor skin irritation with prolonged or repeated contact
Serious Eye Damage/Irritation: May cause significant irritation, redness, tearing
Respiratory or Skin Sensitization: Not classified as sensitizer, but repeated exposure may cause allergic reactions in sensitive individuals
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not listed or classified as carcinogenic, mutagenic, or toxic to reproduction by NTP, IARC, OSHA
STOT (Single Exposure): May cause drowsiness or dizziness
Chronic Effects: Prolonged exposure may impact liver or kidney function based on analog studies; specific long-term data lacking
Toxicity to Aquatic Life: Data on 2,3,4-Trimethoxybenzaldehyde limited, but structurally similar compounds show moderate toxicity to aquatic invertebrates and algae
Persistence and Degradability: Limited biodegradation information, likely slowly biodegradable based on chemical structure
Bioaccumulative Potential: Not expected to bioaccumulate significantly
Mobility in Soil: Likely exhibits low mobility in soil due to low water solubility
Other Adverse Effects: Avoid release to environment as precaution
Waste Treatment Methods: Incinerate in accordance with local, state, and federal regulations. Do not dump in sewers, on the ground, or into any body of water.
Packing and Labeling: Use appropriate containers, label accurately to reflect contents and hazards.
Contaminated Packaging: Triple rinse containers and dispose as hazardous waste if possible.
UN Number: Not applicable as not regulated under standard transport statutes
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not classified as hazardous for transport based on current knowledge
Packing Group: Not applicable
Environmental Hazards: Not designated as marine pollutant
Special Precautions for User: Use spill-proof containers and follow general safety protocols for chemicals during transit
OSHA Status: Not specifically listed as hazardous chemical under OSHA regulations, but general duty clause applies
TSCA (Toxic Substances Control Act): Substance listed in chemical inventory
SARA Title III: Not subject to reporting under Sections 302, 304, or 313
California Proposition 65: Not listed as causing cancer, birth defects, or reproductive harm
REACH Status: Check for updated status within ECHA database
Other Information: Ensure compliance with regional and national regulations concerning chemical safety, environmental protection, and worker health.
